Valine - Benefits, Deficiency Symptoms And Food Sources
What is Valine ?
Valine is an amino acid obtained by hydrolysis of proteins and was first isolated by the German chemist Emil Fischer in 1901 from casein and is not only an essential amino acid but is also a branched-chain amino acid ( the others are isoleucine and leucine) found in high concentration in the muscles. Valine is a member of the branched-chain amino acid family, along with leucine and isoleucine. The three branched-chain amino acids constitute approximately 70 percent of the amino acids in the body proteins. As such, their value in the formation and maintenance of structural and functional integrity in humans is unmeasured.
Uses and Benefits of Valine
Valine, an essential amino acid, has a stimulant effect. It is needed for muscle metabolism, tissue repair, and the maintenance of a proper nitrogen balance in the body. Valine is found in high concentrations in muscle tissue. It is one of the branched-chain amino acids, which means that it can be used as an energy source by muscle tissue. It may be helpful in treating liver and gallbladder disease, and it is good for correcting the type of severe amino acid deficiencies that can be caused by drug addiction.
Deficiency Symptoms of Valine
Maple syrup urine disease (MSUD) is caused by the inability to metabolize leucine, isoleucine, and valine. The disease is so named because urine from affected people smells like maple syrup. A deficiency may affect the myelin covering of the nerves.
Recommended Dosage of Valine
Recommended Dietary Allowance (RDA) of Valine are :-
Rich Food Sources of ValineRich Food Sources of valine include dairy products, grains, meat, mushrooms, peanuts, and soy protein. Supplemental L-valine should always be taken in balance with the other branched-chain amino acids, L-isoleucine and L-leucine.
Caution and Side effectsAn excessively high level of valine may lead to such symptoms as a crawling sensation in the skin and even hallucinations.
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