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Home :: Wilson's disease

Wilson's Disease

Wilson's disease, also called hepatolenticular degeneration or inherited copper toxicosis, is a rare inherited disorder that affects approximately 1 in 30,000 persons worldwide. In persons with Wilson's disease, the body is unable to metabolize the trace element copper as it should, with the result that excess copper accumulates in the brain, kidneys, liver, and the corneas of the eyes. This causes organ damage and other complications, including neurological problems and psychotic behavior. Untreated, Wilson's disease leads to brain damage, cirrhosis of the liver, hepatitis, and, ultimately, death. Fortunately, early detection and treatment of the disease can minimize the symptoms and complications and possibly even prevent them altogether.

What causes Wilson's disease?

It is mainly the liver that controls levels of copper in the body by excreting (getting rid of) excess copper mostly in the bile.

In Wilson's disease this process fails, causing copper to build up in the body. This mainly damages the liver but can also affect other organs, especially the brain.

Symptoms of Wilson's Disease

Symptoms of Wilson's disease may include bloody vomit; difficulty speaking, swallowing, and/or walking; drooling; an enlarged spleen; jaundice; loss of appetite; loss of coordination; progressive fatigue and/ or weakness; progressive intellectual impairment; psychological deterioration manifested as personality changes and/or bizarre behavior; rigidity, spasms, or tremors of the muscles; swelling and/ or fluid accumulation in the abdomen; and unexplained weight loss. Sometimes the first sign is the development of a pigmented ring, known as a Kayser-Fleischer ring, at the outer margin of the cornea, which may be detected during a routine eye examination. In the advanced stages of the disease, symptoms due to chronic active hepatitis or cirrhosis may appear, menstrual cycles may cease, and an individual may experience chest pains, heart palpitations, lightheadedness, pallor, and shortness of breath as a result of exertion.

Although persons with Wilson's disease are born with the disorder, but symptoms usually appear between the ages of 6 and 20 years, but sometimes not until the age of 30, and in rare instances up to age 50.

Vitamins and nutrients to cure Wilson's Disease

Supplement
Suggested dosage
Comments
Vitamin C with bioflavonoids 3,000-5,000 mg daily
in divided doses.
Protects against inflammation, anemia, and hepatitis, and reduces copper levels in the body. Use an esterified form.
Zinc 75 mg daily. Do not exceed this amount Decreases copper levels and enhances immunity. Zinc balances copper in the body
Calcium and magnesium 1,500-2,000 mg daily
750-1,000 mg daily
Minerals that work together to prevent muscle spasms
Vitamin E 600 IU daily. Take separately from iron Promotes normal healing and prevents cell damage. Use d-alpha-tocopherol form

Wilson's Disease treatment

  • Burdock, dandelion, milk thistle, and suma cleanse and support the liver and help to fight fatigue.
  • Black radish and red clover strengthen the liver.
  • Cayenne (capsicum) eases blood pressure, fights fatigue, and helps support the nervous system.
  • St. John's wort is beneficial for the nervous system arid also helps to overcome fatigue and difficulty swallowing.
  • Valerian root is calming and is good for the brain and nervous system. It can also be beneficial for swallowing difficulties.
  • Alfalfa, ginkgo biloba, gotu kola, kava, lobelia, parsley, oat straw, periwinkle, and skullcap are good for overall good health and the functioning of the brain and nervous system. Caution: Do not take lobelia internally on an ongoing basis.
  • Increase your consumption of onions. They contain sulfur, which helps to rid the body of copper.
Considerations and prevention tips
  • Eat fresh (not canned) pineapple frequently. It contains bromelain, an enzyme that helps to keep down swelling and inflammation.
  • If you take a multivitamin and/ or mineral supplement, be sure to choose a formula that does not contain copper.
  • If you suffer from tremors, avoid caffeine.
  • Elevated copper levels in the body result in the depletion of vitamin C and zinc. Persons with Wilson's disease therefore always require a higher than normal intake of these nutrients.
  • Anyone with a family history of Wilson's disease should undergo diagnostic testing-the sooner the better, and whether or not symptoms are present-so that treatment, if necessary, may begin as soon as possible.


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